Vitamin D supplements were linked with lower dementia incidence and longer dementia-free survival, prospective data showed.
In a sample of 12,000 older adults, exposure to vitamin D supplementation was associated with a 40% lower dementia incidence rate compared with no exposure (adjusted HR 0.60, 95% CI 0.55-0.65), reported Zahinoor Ismail, MD, of the University of Calgary in Canada and the University of Exeter in England, and co-authors.
Results were consistent across three vitamin D formulations, the researchers wrote in Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring. Effects were greater in females, in apolipoprotein E ε4 (APOE4)