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Lower Dementia Incidence Linked With Vitamin D Supplements

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Vitamin D supplements were linked with lower dementia incidence and longer dementia-free survival, prospective data showed.

In a sample of 12,000 older adults, exposure to vitamin D supplementation was associated with a 40% lower dementia incidence rate compared with no exposure (adjusted HR 0.60, 95% CI 0.55-0.65), reported Zahinoor Ismail, MD, of the University of Calgary in Canada and the University of Exeter in England, and co-authors.

Results were consistent across three vitamin D formulations, the researchers wrote in Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring. Effects were greater in females, in apolipoprotein E ε4 (APOE4)

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Vitamin D supplements linked to 40% lower incidence

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Scientists say there may be an interesting link between vitamin D supplements and dementia. Anastasiia Stiahailo/Getty Images
  • Researchers assessed the association between vitamin D supplementation and the incidence of dementia.
  • They found that vitamin D supplementation was linked to a lower dementia incidence.
  • Further studies are needed to certify the results.

Over 55 million people live with dementia worldwide, which is expected to rise to 139 million by 2050. There are currently no medications that can stop or reverse the condition.

Interventions that can affect dementia risk factors are being explored to slow disease progression.

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